Marjorie Dawes of Fat Fighters: Are you fat because you're a lesbian, or are you a lesbian because you're fat?

Rosie O'Donnell: What does that mean? What do you mean by that?

Marjorie: Well, I mean, did you find that it was hard to get a man because of the weight? And then think, "Maybe I'll go lezzie?" Or --

Rosie: Marjorie, no, no. Personally, I think that you're born gay. But I'm proud of who I am. I'm a lesbian woman. I'm in a relationship. My partner and I have 4 beautiful children, so.... [group applause] Thank you.

Marjorie: She must have bought those in Africa.... Can we just not go on about her sexuality, please? ... Let's just stick to why she's so fat.

Comedian Rosie O'Donnell on HBO's new show "Little Britain USA." O'Donnell is the first American guest star to appear on the comedy sketch show during a segment where she's confronted by perpetually rude Marjorie Dawes, a counselor for the weight-loss group Fat Fighters. The shows two stars, David Walliams and openly-gay actor Matt Lucas, are basically creating a 4th season for their large collection of insulting characters who step way beyond the boundary lines of race, age, gender, weight, and GLBT stereotypes like Daffyd Thomas, the Only Gay in the Village, and Emily Howard, a transvestite who fruitlessly insists on being treated as a lady . (HBO) A UK tabloid claims that some gay activists in the US are allegedly upset by the material the show will cover, which is to include a 2-minute locker room sketch of full-frontal male nudity. (Daily Star) Other guest stars to appear in this season's episodes include Sting, Paul Rudd, Harry Lennix, and Vivica A Fox, and will be directed in-part by David Schwimmer.