A two-time audience award-winner at this year’s Capital Fringe Festival, Sarah Kane’s 4.48 Psychosis revolves around a woman driven to reassemble the fragments of a life plagued by unsuccessful therapies and endless medications. It was Kane’s final play before committing suicide at the age of 28. The new local theater collective Factory 449 stages the production, directed by John Moletress. Opens Thursday, Oct. 8, at 8 p.m. To. Oct. 25. Warehouse, 1021 Seventh St. NW. Tickets are $20. Call 202-783-3933 or visit www.warehousetheater.com.